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Why do I need intravenous (IV) iron therapy?

Your blood test results have shown that the amount of iron you have in your blood is low.

The most common way to treat low iron levels are through diet and taking iron as a supplementary medicine, either as a tablet or liquid.

However, some people may need to be given intravenous iron straight into the body, by an infusion into a vein. This may be needed if:

  • you cannot take iron tablets or liquid
  • you are not responding to or absorbing your iron tablets or liquid
  • you have chronic heart failure

Having intravenous iron allows for a much larger dose of iron to be given than in tablet or liquid form. 

All medications can carry a risk of side effects and reaction. Prior to receiving your treatment, the nurse caring for you will discuss these and ensure you understand the information provided.

Why iron is important

Iron is an essential mineral your body needs to make red blood cells. Your red blood cells carry oxygen around your body. If you do not have enough iron, you can develop iron deficiency anaemia.

If you are anaemic, you can develop symptoms which may include:

  • shortness of breath
  • lack of energy
  • tiredness
  • feeling faint or dizzy
  • noticeable heartbeats (heart palpitations)
  • low mood
  • pale skin

Do I still need to take iron tablets or liquid?

If you are taking either iron tablets or liquid these will need to be stopped before you have your iron infusion. We recommend that these are stopped 48 hours in advance of your infusion.

They are not usually required after your infusion, but you will be advised by the nurse caring for you if you need to restart your iron tablets or liquid again.

Warning

When IV therapy is inappropriate

You should not have an intravenous iron infusion if:

  • you are known to be sensitive/ allergic to any of the ingredients used for the intravenous iron
  • you have any liver disease or abnormal liver function blood tests
  • you have any new or ongoing infections
  • your anaemia is not because of a shortage of iron

Risks and side effects

Generally intravenous iron is a safe and effective treatment to have. However, there may be some side effects from the treatment you could experience.

It is important to immediately tell the nurse caring for you if:

  • you feel unwell before, during or after the treatment
  • you experience any discomfort, burning, swelling or redness around the cannula site

Sometimes side effects can occur one to two days after the infusion, these generally settle down without any need for further treatments. However, if you are worried about any side effects, you can talk to your GP, or if you are a patient being cared for by the palliative care team contact the Palliative Care Advice Line on 0330 1588011.

If you have chest pain, difficulty breathing, neck or face swelling call 999 for an ambulance.

Common side effects

Common side effects can include:

  • headaches
  • feeling sick or vomiting
  • aching pains in the joints or muscles
  • a metallic taste in the mouth
  • changes to your blood pressure or pulse
  • brown skin staining around the cannula site if the infusion leaks into your surrounding tissues. This may be long lasting or permanent

Rare side effects

Rarely you can experience a more serious allergic reaction to the infusion. If this should happen you may experience symptoms of:

  • feeling dizzy, lightheaded or faint
  • a fast pulse
  • swelling to your face, lips, tongue, throat or body
  • difficulty breathing
  • chest pains
  • itchy skin, a rash or skin redness

What does the infusion involve?

The infusion is given in a medical setting such as an inpatient ward area or an outpatient clinic.

A canula, which is a thin plastic tube, is inserted into a vein on your hand or arm. The infusion is then attached to this and the iron solution is dripped into your body over a short period of time. It can take up to 60 minutes to complete the infusion.

Following the infusion, you will be asked to rest for 30 minutes. If you feel well you will then be able to go home.

Before, during and after the infusion nurses will closely monitor you. They will take your temperature, blood pressure, pulse, oxygen levels and respiration rate to ensure you are not experiencing side effects or reacting to the iron infusion.

How often will I need an iron infusion?

Sometimes you will need two iron infusions, given at least one week apart. This is so that your iron stores in your blood are fully topped up.

The nurses or your GP will continue to monitor your blood results regularly. Should your iron levels become low again, you may need to have further iron infusions.

How quickly does the treatment work?

Most people start to feel their energy levels increase within a couple of weeks, but this can vary from person to person. It is not anticipated that your iron infusion will affect your ability to undertake usual activities.

Any further questions?

If you have any further questions about this treatment, discuss them with the nurse or doctor caring for you.

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